Gene description for PLK2
Gene name polo like kinase 2
Gene symbol PLK2
Other names/aliases -
Species Bos taurus
 Experiment description of studies that identified PLK2 in Bovine milk

1
Experiment ID439
Identified moleculeprotein
Extracellular vesicle typeExosomes/Membrane vesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 22129587   
OrganismBos taurus
Experiment descriptionBovine milk exosome proteome.
AuthorsReinhardt TA, Lippolis JD, Nonnecke BJ, Sacco RE.
Journal name J Proteomics
Publication year2012
SampleBovine milk
Sample nameNormal cow-Milk
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV120041: EV-METRIC:56%

2
Experiment ID2815
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 34168137   
OrganismBos taurus
Experiment descriptionOral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis
AuthorsSamuel M, Fonseka P, Sanwlani R, Gangoda L, Chee SH, Keerthikumar S, Spurling A, Chitti SV, Zanker D, Ang CS, Atukorala I, Kang T, Shahi S, Marzan AL, Nedeva C, Vennin C, Lucas MC, Cheng L, Herrmann D, Pathan M, Chisanga D, Warren SC, Zhao K, Abraham N, Anand S, Boukouris S, Adda CG, Jiang L, Shekhar TM, Baschuk N, Hawkins CJ, Johnston AJ, Orian JM, Hoogenraad NJ, Poon IK, Hill AF, Jois M, Timpson P, Parker BS, Mathivanan S.
Journal name Nat Commun
Publication year2021
SampleBovine milk
Sample nameRaw milk
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
mRNA
miRNA
tRNA
Methods used in the studyWestern blotting
Mass spectrometry
Small RNA sequencing
EV-TRACK -

3
Experiment ID2822
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 34168137   
OrganismBos taurus
Experiment descriptionOral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis
AuthorsSamuel M, Fonseka P, Sanwlani R, Gangoda L, Chee SH, Keerthikumar S, Spurling A, Chitti SV, Zanker D, Ang CS, Atukorala I, Kang T, Shahi S, Marzan AL, Nedeva C, Vennin C, Lucas MC, Cheng L, Herrmann D, Pathan M, Chisanga D, Warren SC, Zhao K, Abraham N, Anand S, Boukouris S, Adda CG, Jiang L, Shekhar TM, Baschuk N, Hawkins CJ, Johnston AJ, Orian JM, Hoogenraad NJ, Poon IK, Hill AF, Jois M, Timpson P, Parker BS, Mathivanan S.
Journal name Nat Commun
Publication year2021
SampleBovine milk
Sample nameCommercial milk
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
mRNA
miRNA
tRNA
Methods used in the studyMass spectrometry
Small RNA sequencing
EV-TRACK -

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